Anti-Gastric Ulcer Mechanism of Anredera scandens (L.) Moq Leaves Extract

Dewa Ayu Swastini,S.F.,M.Farm.,Apt, DEWA AYU SWASTINI and apt. PUTU OKA SAMIRANA, S.Farm., M.Sc., PUTU OKA SAMIRANA and NI KADEK WARDITIANI.S.Farm.M.Sc,Apt, NI KADEK WARDITIANI (2019) Anti-Gastric Ulcer Mechanism of Anredera scandens (L.) Moq Leaves Extract. International Journal of Pharmaceutical Sciences and Research, 11` (8). ISSN 09751459

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Abstract

Anredera scandens (L.) Moq. is one of the plants that have gastric ulcer activity. This study aimed to determine the anti-ulcer mechanism of Anandera scandens (L.). Moq leaves ethanol extract (AEE). Ulcer modeling was made using aspirin-induced Wistar strain male rats. The mechanism investigated by its ability to inhibit gastric acid secretion, reduce the diameter of the wound, and increase gastric volume after being treated for 14 days. Based on the test results, the AEE. At a dose of 250 mg/kg BW, 300 mg/kg BW, and 350 mg/kg BW, has been able to increase the pH of the gastric to become more alkaline, reduce the diameter of peptic ulcers, and increase mucous cell proliferation (p <0.05).

Item Type:	Article
Subjects:	L Education > L Education (General)
Divisions:	Faculty of Law, Arts and Social Sciences > School of Education
Depositing User:	USDI USDI Universitas Udayana
Date Deposited:	20 Jul 2020 12:24
Last Modified:	20 Jul 2020 12:24
URI:	https://erepo.unud.ac.id/id/eprint/32294

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